Motif ID: STAT5{A,B}.p2

Z-value: 1.340


Transcription factors associated with STAT5{A,B}.p2:

Gene SymbolEntrez IDGene Name
STAT5A 6776 signal transducer and activator of transcription 5A
STAT5B 6777 signal transducer and activator of transcription 5B



Activity profile for motif STAT5{A,B}.p2.

activity profile for motif STAT5{A,B}.p2


Sorted Z-values histogram for motif STAT5{A,B}.p2

Sorted Z-values for motif STAT5{A,B}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT5{A,B}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_22305570 2.327 NM_005015
OXA1L
oxidase (cytochrome c) assembly 1-like
chr19_+_49361054 2.216 NM_001146220
NM_001032373
NM_001032374
NM_015919
NM_001032372
ZNF226




zinc finger protein 226




chr14_+_23700261 1.990 NM_006084
IRF9
interferon regulatory factor 9
chr6_+_139136349 1.975 NM_015439
CCDC28A
coiled-coil domain containing 28A
chr14_-_19951417 1.975 NM_007110
TEP1
telomerase-associated protein 1
chr19_+_49309350 1.939 NM_013362
ZNF225
zinc finger protein 225
chr17_+_36515166 1.810 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr19_-_49552638 1.779 NM_001083335
NM_013380
ZFP112

zinc finger protein 112 homolog (mouse)

chr19_+_49198916 1.778 NM_006300
ZNF230
zinc finger protein 230
chr20_-_18425811 1.726 NM_006606
RBBP9
retinoblastoma binding protein 9
chr19_+_49290319 1.664 NM_013398
ZNF224
zinc finger protein 224
chr2_-_142605010 1.654 LRP1B
low density lipoprotein receptor-related protein 1B
chr9_+_103200939 1.592 NM_003452
NM_197977
ZNF189

zinc finger protein 189

chr19_-_51058177 1.568 NM_004819
SYMPK
symplekin
chr2_+_95194903 1.563 NM_001017396
NM_021088
ZNF2

zinc finger protein 2

chr16_-_69030421 1.558 NM_006927
ST3GAL2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr19_-_49131250 1.555 NM_003425
ZNF45
zinc finger protein 45
chr2_+_95195260 1.505 ZNF2
zinc finger protein 2
chr2_-_85435074 1.484 NM_017750
RETSAT
retinol saturase (all-trans-retinol 13,14-reductase)
chr19_-_62680703 1.481 NM_001024596
NM_001144068
ZNF772

zinc finger protein 772


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 14 of 14 entries
Enrichment   P-value GO Accession GO Term
96.76 1.36e-02 GO:0042572 retinol metabolic process
4.64 4.83e-07 GO:0006355 regulation of transcription, DNA-dependent
4.47 8.64e-07 GO:0051252 regulation of RNA metabolic process
4.19 2.34e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
4.08 3.48e-06 GO:0010556 regulation of macromolecule biosynthetic process
4.02 1.31e-06 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.96 5.47e-06 GO:0010468 regulation of gene expression
3.90 2.11e-06 GO:0051171 regulation of nitrogen compound metabolic process
3.80 1.04e-05 GO:0031326 regulation of cellular biosynthetic process
3.75 1.23e-05 GO:0009889 regulation of biosynthetic process
3.21 1.64e-05 GO:0080090 regulation of primary metabolic process
3.20 4.77e-05 GO:0060255 regulation of macromolecule metabolic process
3.17 2.06e-05 GO:0031323 regulation of cellular metabolic process
2.87 1.00e-04 GO:0019222 regulation of metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
2.18 1.35e-03 GO:0005634 nucleus
1.88 8.83e-06 GO:0043231 intracellular membrane-bounded organelle
1.88 9.09e-06 GO:0043227 membrane-bounded organelle
1.75 1.23e-05 GO:0043229 intracellular organelle
1.75 1.29e-05 GO:0043226 organelle
1.49 1.32e-03 GO:0044424 intracellular part
1.46 2.70e-03 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
4.74 7.25e-08 GO:0008270 zinc ion binding
4.41 5.85e-08 GO:0003677 DNA binding
4.16 5.28e-07 GO:0046914 transition metal ion binding
3.11 1.55e-05 GO:0003676 nucleic acid binding
2.63 1.97e-04 GO:0046872 metal ion binding
2.60 2.32e-04 GO:0043169 cation binding
2.60 2.40e-04 GO:0043167 ion binding